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KMID : 1037420160110020059
Journal of Korean Skull Base Society
2016 Volume.11 No. 2 p.59 ~ p.64
Effectiveness of collagen matrix underlay graft technique for CSF sealing in posterior fossa surgery
Jeong Eun-Oh

Kim Seon-Hwan
Lim Jeong-Wook
Kwon Hyon-Jo
Choi Seung-Won
Koh Hyeon-Song
Youm Jin-Young
Song Shi-Hun
Abstract
Objective : Complete protection from CSF(cerebrospinal fluid) leakage after posterior fossa surgery was difficult, although many variable methods has been performed. Collagen matrix is product to protect dura defect and prevent CSF leakage. The authors performed collagen matrix underlay graft and identified effectiveness of this technique for CSF sealing.
Methods : The authors evaluated 92 posterior fossa surgery used fibrin glue, polyethylene glycol (PEG) sealant, fibrinogen based collagen fleece, collagen matrix between January 2006 and December 2015. CSF leakage incidence according to use of variable dura sealing materials was assessed.

Results : CSF leakage occurred 8 cases(8.7%) in 92 posterior fossa surgery. CSF leakage didn¡¯t occur in 42 cases underwent collagen matrix underlay graft. Cases of fibrin glue, polyethylene glycol(PEG) sealant, fibrinogen based collagen fleece had effect of CSF leakage block, however didn¡¯t have significant difference according to use of this materials.

Conclusion : Collagen matrix underlay graft after posterior fossa surgery didn¡¯t have complication such as chemical injury and infection and had effect of CSF sealing.
KEYWORD
CSF leakage, Posterior fossa, Collagen matrix
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